Cần Thơ, anglicized as Can Tho or Cantho, is the fourth-largest city in Vietnam, and the largest city along the Mekong Delta region in Vietna…Cần Thơ, anglicized as Can Tho or Cantho, is the fourth-largest city in Vietnam, and the largest city along the Mekong Delta region in Vietnam. It is noted for its floating markets, rice paper-making village, and picturesque rural canals. It has a population of around 1.507.187 as of 2024, and is located on the south bank of the Hậu River, a distributary of the Mekong River. In 2007, about 50 people died when the Cần Thơ Bridge collapsed, causing Vietnam's worst engineering disaster. In 2011, Cần Thơ International Airport opened.