The Wheeling, WV–OH Metropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of two counties in the Northern Panhandle of West Virginia and one in eastern Ohio, anchored by the city of Wheeling. As of the 2010 census, the MSA had a population of 147,950. This represents a decline of 3.4% from the 2000 census …The Wheeling, WV–OH Metropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of two counties in the Northern Panhandle of West Virginia and one in eastern Ohio, anchored by the city of Wheeling. As of the 2010 census, the MSA had a population of 147,950. This represents a decline of 3.4% from the 2000 census population of 153,172.