This variant, which usually affects people of a younger age, is frequently associated with mutations located within the P2 region of the alpha-synuclein, such as the G51D mutation, which produces ...

A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations. Our meta-analysis ...

"Our study highlights how assay design can markedly improve the measurement of disease-related alpha-synuclein aggregates across a variety of clinically relevant samples," says Beauchemin.

Researchers have discovered a new biomarker for Parkinson’s that could be used to identify people at risk of the disease and profoundly change the way it is treated. The assay for a particular ...

Eisai forges drug discovery alliance with UK biotech Wren Therapeutics on alpha-synuclein drugs for Parkinson’s, dementia with Lewy bodies ...