New research has found a novel target with therapeutic potential for metastatic eye melanoma—an aggressive eye cancer—with ...

Researchers used CRISPR to find a pair of genes that show strong potential as a new therapeutic target for uveal melanoma – a ...

In vivo CRISPR-Cas9 screen sheds light on cancer metastasis, tumor evolution. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2015 / 03 / 150305125533.htm ...

In vivo CRISPR-Cas9 screen sheds light on cancer metastasis and tumor evolution Genome-scale study points to drivers of tumor evolution and metastasis, provides roadmap for future in vivo Cas9 screens ...

But new research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which ...

An artistic rendering of CRISPR-enhanced T-cells attacking a tumor. Research has shown that the gene-editing system CRISPR can modulate T cell behavior to make them better cancer killers without ...

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily ...

The Wellcome Sanger-led team used CRISPR-Cas9 to screen over 18,000 genes in more ... identify those that are crucial to cancer survival or growth. “With CRISPR we have discovered a very ...

In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A ...

Using CRISPR/Cas9, scientists created a new high-throughput screening tool for studying the development and progression of liver cancer in mice. [Ernesto del Aguila III, NHGRI] ...