CRISPR libraries enable scientists to systematically investigate gene functions, identify novel drug targets, and develop personalized therapies.

Researchers found that mutations in the PPP2R1A gene make ovarian clear cell carcinoma (OCCC) cells sensitive to ATR inhibitors. This discovery could help identify patients who would benefit from ATR ...

First, investigators performed a genome-wide CRISPR knockout screen to identify proteins that ... but we're trying to reprogram cells that the cancer managed to recruit back to being anti-tumor ...

Genetic engineering has revolutionized biomedical research, but optimizing these gene-editing tools remains a challenge. Scientists have now developed a novel approach using an enhanced version of ...

CRISPR leaders came together to celebrate the one-year anniversary of the Danaher-IGI Beacon for CRISPR Cures collaboration, ...

including cancer. The findings are published in the journal Nature Biomedical Engineering. Gene editing technologies allow scientists to use enzymes—in this case, Cas9 (CRISPR-associated protein ...

Moving forward, Guan and his team plan to explore whether p47 limits metastasis for other cancer types. Beyond that, they have another 37 genes from their CRISPR-Cas9 screen to scrutinize. Autophagy’s ...

The lab reportedly will be the first center to offer arrayed CRISPR screening on this scale for chronic disease through collaborations with researchers from across the U.K. This will enable more ...

CRISPR has made it cheap and easy. How CRISPR therapy could cure everything from cancer to infertility The imminent approval of the world's first CRISPR treatment for sickle cell disease is just ...