Enter a CRISPRi-based screen Kampmann previously used to analyze 2D cultures of iPSC-derived neurons (Kampmann et al., 2019). The scientists ran this screen in the iAssembloids, suppressing thousands ...

In addition, the researchers used CRISPRi to screen macrophage lncRNA for involvement in inflammation. Unexpectedly, they located a region that is multifunctional and can work as an RNA as well as ...

CRISPR interference (CRISPRi) is a novel method for specific gene knockdown. It's CRISPR, without the cut. The Horizon CRISPRi system uses a deactivated Cas9 nuclease (dCas9) fused to our proprietary ...