ISGylation induction decreases MVB numbers and impairs exosome secretion. Using ISG15-knockout mice and mice expressing the enzymatically inactive form of the de-ISGylase USP18, we demonstrate in ...

High centrifugal force can damage exosome integrity Charge neutralization-based precipitation (commercial kits) 32,33 Based on the principle of compound polymerization precipitation. Samples are mixed ...

However, ILVs also form in the absence of ESCRTs ... carry MHC-peptide complexes recognized by T lymphocytes. Secretion of those exosomes could promote antitumor immune responses.

8 “Live reporters like these can reveal unexpected cellular behaviors by allowing real-time visualization of the secretion and interaction of exosomes with cells. Although we know exosomes are ...

This segment turned out to be an 18-amino-acid sequence, which the team termed Exosome Binding Peptide (EBP). The team found that “addition of EBP to an unrelated protein directed secretion on ...

A review led by Academician Yulong Yin from the Institute of Subtropical Agriculture of the Chinese Academy of Sciences has shed new light on the intricate interplay between exosomes and autophagy ...

"The phase-specific exosome secretion of LIFES meets physiological requirements, which aligns with the native multi-target and multi-stage paracrine regulation effects observed in physiological ...

Researchers have now identified a microRNA, miR-940, that is abundant in exosomes secreted by prostate cancer cells and can trigger bone-forming lesions in mice. The findings indicate that ...

and exosomes, as mediators of intercellular communication, have become a major focus of research. "This paper focuses on the theme of how autophagy-dependent secretion regulates autophagy itself ...

Basically, exosomes are like a cell’s text message—but instead of words or emojis, they contain data in the form of proteins, lipids, growth factors, and RNA. “In skincare, exosomes are ...