Tumors contain a fraction of cancer stem cells that maintain the propagation of the disease. The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to be enriched leukemic ...

Acute myeloid leukemia (AML) is a heterogeneous group ... We used oligonucleotide-based DNA microarrays to study global gene expression in ten AML+8 patients with +8 as the sole chromosomal ...

Recent progress in the molecular genetics of acute myeloid leukemia (AML) has shown this disease to be more heterogeneous than previously realized. Recurrent cytogenetic and mutational changes in ...

They classified acute myeloid leukemia cells by their resemblance to gene expression of stem cells at different life stages, discovering that the normal stem cell age most reflective of leukemia ...

Oct. 9, 2024 — Researchers have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene ... by which acute myeloid leukemia ...

Galinpepimut-S therapy showed specific T-Cell immune responses for patients with acute myeloid leukemia in remission ...

Mikkael A. Sekeres, MD, Sylvester Comprehensive Cancer Center, discusses the potential benefits of treosulfan, a newly ...

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Dr. Cecilia Yeung’s research focuses on genomic changes, clonal evolution, and epigenetic control of gene expression in myeloid neoplasms (MDS, MPN and AML) and she has developed research expertise in ...

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the ...

The basis of peptide vaccination is the observation that leukemia ... protein expression of PR-3. [39] Taken together, these DC vaccination studies demonstrated that DC vaccination in AML patients ...

Dr. Radich specializes in developing methods to improve the detection and treatment of chronic and acute myeloid leukemias ... and relapse in hematological malignancies, performing gene expression and ...