began with a genome-wide genetic screen based on CRISPR interference (CRISPRi) that systemically reduces the expression of every single gene in the genome of a pluripotent stem cell (PSC ...

Horizon Discovery leads the way in offering a broad range of CRISPR screening services from initial design and cell-line selection to bioinformatic analysis of the screen results. What is CRISPR ...

Combining our CRISPR screening technologies provides a more detailed overview: running CRISPRa and CRISPRi screening in parallel allows us to identify ‘switch’ genes that display contrasting ...

In the study, "Targeting the SHOC2–RAS interaction in RAS-mutant cancers," published in Nature, researchers conducted a genome-wide CRISPR screen to identify genetic dependencies associated with ...