The four colony-stimulating factors (CSFs) are glycoproteins that regulate the generation and some functions of infection-protective granulocytes and macrophages. Recombinant granulocyte-CSF (G ...
In a paper published in Science Bulletin, multi-omics analyses comprising of lipidomics (439 lipids), sterolomics (22 ...
Gilde Healthcare Leads Series B Extension, Joining Premier Syndicate of Leading Life Science InvestorsFunding Supports Registrational Phase 3 ...
Additions of Elyse Seltzer, M.D., as CMO and Robert Francomano as CCO Strengthen Company’s Presence in the U.S.Seasoned Team to Drive Forward ...
These TAMs are polarized toward the M2 phenotype by CSF-1 and CCL2 ... 2011 Expert Reviews Ltd. Cite this: Tumor-associated Macrophages in Breast Cancer as Potential Biomarkers for New Treatments ...
The team has focused on two proteins that are essential to the immune system: one is IFNalpha2a, which has powerful antiviral and anti-cancer effects, and the other is macrophage-CSF, which is ...
Savara Inc. (Nasdaq: SVRA) (the Company), a clinical stage biopharmaceutical company focused on rare respiratory diseases, reported financial results for the third ...
Alveolar macrophages need to be stimulated by granulocyte-macrophage colony-stimulating factor (GM-CSF) to function properly in clearing surfactant, but in autoimmune PAP, GM-CSF is neutralized by ...
Previous research has highlighted the roles of the FGF, CSF, and VEGF signaling pathways in the pathology of MS. “In chronic ...
Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...
Alveolar macrophages need to be stimulated by granulocyte-macrophage colony-stimulating factor (GM-CSF) to function properly in clearing surfactant, but in autoimmune PAP, GM-CSF is neutralized by ...
The presence of the CSF-1 receptor may identify both macrophages, as well as CSF-1-producing tumor cells. Identification of the CSF-1 receptor by immunohistochemistry in human breast tumors is ...