"It's the first time a role for membrane fusion has been described for this complex and it's a breakthrough in how we think about the way the exocyst complex works," said Mary Munson, Ph.D ...

Secreted vesicles known as exosomes were first discovered nearly 30 years ago. But, considered little more than garbage cans whose job was to discard unwanted cellular components, these small vesicles ...

Evox is engineering exosomes—lipid-membrane-containing nanoparticles constitutively produced by cells—and loading them with protein therapeutics or nucleic-acid-based agents (Fig. 1).

Three peptides, short chains of ‘mini-proteins’ called amino acids, are attached to the membrane of each exosome. One directs the exosome to home in on a specific site in the body; another ...

Proteoliposomes were efficiently prepared by cell-free membrane protein synthesis with liposome chaperone (artificial cell method) for bio-analysis and DDS. New strategy for functionalization of ...

Their approach is to attach three peptides - short amino acid chains - to the membrane of each exosome. One is a homing peptide, which directs the exosome to bind to a specific site in the body.

Exosome formation is a multistep process that begins with the inward budding of the plasma membrane to form early endosomes. These endosomes mature into multivesicular bodies (MVBs), which either ...

Their approach is to attach three peptides — short amino acid chains — to the membrane of each exosome. One is a homing peptide, which directs the exosome to bind to a specific site in the body.