X denotes truncating mutation. PEST2 domain 345–377; UBA domain 387–436. *Two different mutations reported to cause this truncation. ‡ Results from splice site mutations (intron 7).

Also known as osteitis deformans, it is a chronic bone disorder. When someone has Paget’s disease, it means the process of bone remodeling, which is the cycle of bone growth, has become abnormal.

Paget’s disease of the breast is a rare kind of breast cancer that mostly affects the skin around the nipple. It happens in only a small number of breast cancer cases because it’s linked to ...

Paget’s disease of the vulva is a rare type of skin disease that develops on the vulva. It is very slow to spread and is typically found in women who have been through menopause. In some cases, ...

Symptoms of breast eczema include a dry, itchy rash. They can improve with home remedies and medical treatments. However, symptoms can resemble those of a rare type of breast cancer called Paget ...

Intensive bisphosphonate treatment does not confer a clinical advantage over treatment of symptoms alone in patients with Paget disease of bone. Findings from a UK study reveal that maintenance of ...

Ipriflavone can block part of the process that leads to bone loss. Ipriflavone can block part of the process that leads to bone loss. A bone disease that can cause pain (Paget disease). Early ...