What was puzzling was why sickle cell anemia was so prevalent in some African populations. How could a "bad" gene-- the mutation that causes the sometimes lethal sickle cell disease -- also be ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated environment of tissue capillary beds, the misshapen RBCs are the cause of all the ...

The causative mutation is the substitution of valine for glutamic acid at the sixth position of the β globin chain (Glu6Val). Sickle cell hemoglobin (HbS) behaves like normal hemoglobin when ...

Sickle cell disease (SCD) is a group of inherited blood disorders resulting from a mutation in the hemoglobin protein in red blood cells. This mutation changes the shape of the blood cells from round, ...

NASHVILLE, Tenn. (WTVF) — One of Vanderbilt's latest studies has found a cure for sickle cell disease. Sickle cell is a blood disorder where the body creates mutated red blood cell proteins.