Infiltrative splenomegaly: Develops when substances that normally don’t enter the spleen, such as proteins and a form of glucose (sugar) called glycogen, enter the spleen and become trapped there.

Thrombocytopenia and splenomegaly often occur together. Thrombocytopenia means that a person has an abnormally low platelet count, while splenomegaly means the spleen is larger than it should be.

Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

Healthcare professionals consider splenomegaly when the spleen is anywhere from 12 to 20 centimeters (cm) (4.7 to 7.9 inches [in]) in length and weighs more than 400 grams (g) (0.88 pounds [lb]).

Since evaluation of splenomegaly still rests for the most part on physical examination however, it is believed that a technic often heretofore neglected in classic teaching should merit consideration.

Splenomegaly is an enlarged spleen. This can cause stomach discomfort, decreased blood flow and filtering, and anemia. It can even lead to a ruptured spleen, so taking precautions and seeing a ...

Splenomegaly, or enlargement of the spleen, is common in patients with Philadelphia-negative myeloproliferative neoplasms, and it is associated with symptoms like early satiety and abdominal pain.

The combination of morphologic and immunohistochemical analyses showing a hybrid endothelial–histiocytic phenotype established the diagnosis of littoral-cell angioma. 1 Primary tumors of the ...

Did you know that certain medications can cause symptom of 'Splenomegaly'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

Splenomegaly retained its negative prognostic role in multivariate analysis of risk factors for thrombosis, as did previous thrombosis, leucocyte count, and male gender.

Hematological diseases can cause massive splenomegaly and portal hypertension via portal vein thrombosis, liver infiltration by malignant cells, or in association with NRH.