Study shows how neurofilaments act like Velcro to clog up brain functions
Northwestern Medicine scientists have uncovered new insights into how neurofilaments act like Velcro in neurodegenerative ...
The Scientist2mon
A STING Operation in Safeguarding Cells from Stress
TFEB is also an ancient regulator of autophagy and innate immunity ... “This paper shows the good and bad activity coming from different parts of the protein. So conceivably, you can selectively ...
Baylor College of Medicine2y
TFEB and V-ATPase-mediated Lysosomal Stress Sensing Pathway in Tauopathy
TFEB targets only the aberrant tau species and this specificity ... and spreading through selective targeting of pathological MAPT (microtubule associated protein Tau). Autophagy 2019; 15(4): 583-98.