Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

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University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of ...

Researchers at the University of Colorado Anschutz Medical Campus have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B ...

Subsequently, CXCR3+ pre-memory B cells differentiated into CXCR3+ memory B cells, which exited the mediastinal lymph nodes and homed to the lung to become lung-BRMs. “In this proposed model, CXCR3+ ...

As a postdoctoral fellow, Martinez-Gonzalez investigated the memory potential of another innate immune cell, type 2 innate lymphoid cells (ILC2s), which are activated by interleukin (IL)-33 and play ...

A new study reveals that neurons in the brain’s memory center, the hippocampus, continue to form well into late adulthood. A ...

Two key players maintain this memory: long-lived plasma cells, which continuously produce antibodies, and memory B cells, which stand ready to adapt to future infections. These B cells are vital for ...