The Pittsburgh Pirates (22-37) visit the San Diego Padres (32-24) for the final game of their 3-game series. First pitch from Petco Park is at 5:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Pirates vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Get San Diego vs Pittsburgh baseball betting preview, spread and over/under insights for their matchup on June 1.

The Pittsburgh Pirates have two untouchables at the MLB trade deadlline, but they are open to trading an All-Star.

PITTSBURGH — Pittsburgh Pirates center fielder Oneil Cruz showed off his great speed and base running skills in the most recent game vs. the San Diego Padres at

Paul Skenes, the Pirates' star pitcher with a 2.15 ERA, is anticipated to start against the Padres tonight at PNC Park. Despite the Pirates' current losing streak and .184 batting average, Skenes' recent dominance offers hope.

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The Pittsburgh Pirates got a great start from left-handed pitcher Bailey Falter and shutout the San Diego Padres in a 5-0 victory at Petco Park. Th

Discover why the Pittsburgh Pirates should trade closer David Bednar before the 2025 deadline and explore a blockbuster proposal.

Get San Diego vs Pittsburgh baseball betting preview, spread and over/under insights for their matchup on May 30.

Down 3-2 in the top of the eighth inning against the San Diego Padres on Friday night, a called third strike against Henry Davis in a 3-2 count with two outs and the bases loaded that was low and would’ve been ball four if the ABS (Automatic Ball-Strike System) was intact,