BACKGROUND: Current outcomes from catheter ablation for scar-dependent ventricular tachycardia (VT) are limited by high ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...

Our vision is to innovate and incorporate promising technologies to communicate freely available, high-priority, high-quality content, which accelerates scientific progress and advances heart and ...

Two main forms of sporadic SVD have been described: arteriolosclerosis and cerebral amyloid angiopathy (CAA). The former describes a group of small vessel pathological processes. Arteriolosclerosis ...

There are a large number of rare ITPR1 missense variants reported in open data repositories. Based on their locations in the ITPR1 channel structure, we selected and characterized 33 human ITPR1 ...

We aim to provide the reader with an overview of the genes and corresponding biological pathways that have been found to be implicated in rare and common forms of SVD. We have elected to categorize ...

Idiopathic VTs occur in patients without structural heart disease and rarely cause sudden death. Electrophysiological study with catheter ablation is often warranted to confirm the diagnosis, to ...

We used the National Cancer Database to identify all patients with PCL between 2004 and 2016; institutional review board approval was obtained. All patients had confirmed primary tumor site in the ...

Abstract We investigated the effects of angiotensin II (Ang II) type 1 receptor blockade with losartan on the renin-angiotensin-aldosterone system in hypertensive patients (supine diastolic blood ...

In the 1960s and 1970s, large, descriptive autopsy studies were conducted, providing classic morphological features of intracranial arteries. Despite the importance of intracranial atherosclerosis to ...

On the basis of the hypothesis that abnormal maternal immunologic response may cause PPCM, Bozkurt et al 11 attempted the use of intravenous immune globulin, which has a significant immune modulator ...