The Cubs swept the City Series last weekend, keeping the White Sox on par with last year’s team for the worst 50-game start in franchise history at 15-35.

See all the player props bets with current odds for the MLB matchup between the Seattle Mariners and White Sox on }{ day_of_week model.date }}, May 21,

CHICAGO – Chase Meidroth has gotten off to a strong start in his rookie season with the White Sox. He enters Wednesday's game against the Mariners on an eight-game hit streak, which has put him near the top of the American League rookie charts.

The Sox (15-34) didn’t falter late in their win over the Mariners after a one-hour, 35-minute rain delay. Powered by six shutout innings from Adrian Houser, who signed and debuted on the same day, the Sox did just enough to squeak by in Tuesday’s win.

MLB player prop bets and odds for Miguel Antonio Vargas on Wednesday, May 21, 2025, as the Chicago White Sox take on the Seattle Mariners.

The second grand slam of Julio Rodriguez’ career and a stellar pitching performance by Luis Castillo helped the Mariners win their fourth game in a row Monday.

The Seattle Mariners got solid injury news on multiple fronts on Saturday. First, Logan Gilbert, out with a Grade 1 flexor strain, threw a bullpen at Petco Park

Logan Evans will start for the Seattle Mariners on Wednesday at Rate Field against Miguel Vargas and the Chicago White Sox. First pitch is at 2:10 p.m. ET for the final game of a three-game series.