Our guide to betting on the NFL in Week 4 has everything you need all in one place, including updated odds, expert predictions and tips for making your weekly pool picks or setting DFS lineups.

The best Week 4 picks for your specific NFL pool depend on strategy factors such as its size, rules, and prize structure. (Our Football Pick 'em Picks product recommends weekly picks for you based ...

Now, the model has simulated the entire Week 4 NFL schedule 10,000 times and generated its optimal NFL pick'em plays. Head to SportsLine to see them now. Top Week 4 NFL office pool predictions One ...

Check out the latest pick'em and confidence pool strategy and advice ahead of Week 4 from PoolGenius, friends of the Sporting News and experts in sports pools and pick'em contests.