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RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.
Professor Won Do Heo's team in the Department of Biological Sciences develops targeted RNA modification technology, the world ...
Subsequently, the CRISPR–Cas13 system has emerged as a potential tool to identify and rectify errors in RNA sequences. CRISPR–Cas13 is a novel technology specifically engineered for virus ...
The CRISPR gene editing technology has transformed the research lab, and this powerful tool is now making its way into the clinic... | Cell And Molecular Biology ...
Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided RNases Cas13. Here, we profile Type VI systems to engineer a Cas13 ortholog capable of robust knockdown and demonstrate ...
Rather than the popular DNA-editing CRISPR-Cas9 technique, the new approach uses CRISPR-Cas13, which can target mRNA—the messenger molecule that carries protein blueprints transcribed from DNA.
Qi and his colleagues used a version of the gene-editing tool CRISPR, called CRISPR-Cas13, to target individual pieces of RNA (unlike the more widely known CRISPR-Cas9, which targets DNA). Typically, ...
Subsequently, the CRISPR–Cas13 system has emerged as a potential tool to identify and rectify errors in RNA sequences. CRISPR–Cas13 is a novel technology is specifically engineered for virus ...