A new project at Purdue University that combines many types of available data in a “digital twin” model of bladder cancer may prove powerful enough to predict patient outcomes.

New research, published recently in Proceedings of the National Academy of Sciences, uncovers the unique dynamics governing the endoplasmic reticulum (ER)’s evolution and addresses the long-standing ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...

We propose a model where a pool of nucleoporins synthesized in the previous cell cycle remains in the cytoplasm after the postmitotic NPC assembly. This Nup pool has to be incorporated into the ...

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Nuclear pore complexes are the guardians of the human genome that is packaged into the nucleus of all cells. They form selective channels through the envelope of the nucleus and connect its ...

We used single-nucleus RNA ... maturation of single-cell sequencing technologies, coupled with increasing accessibility to appropriate donor material, kick-started this project.

Nuclear pore complexes are the guardians of the human genome that is packaged into the nucleus of all cells. They form selective channels through the envelope of the nucleus and connect its interior ...

Landmark single-cell dataset of one billion cells will be used to train new AI models to advance understanding of cellular ...

From the evidence of karyomeres in animal cells, the nucleus is regarded as a compound structure, and it was further suggested that the spindle is also compound, the real unit in mitosis being a ...

Researchers created replicas of 3D cell structures inside Minecraft and made them available for anyone to use in their own installation of the game.