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ascopubs.org22y
Randomized Comparison of Low-Dose Involved-Field Radiotherapy and No Radiotherapy for Children With Hodgkin’s Disease Who Achieve a Complete Response to Chemotherapy
PURPOSE: Current standard therapy for children and adolescents with Hodgkin’s disease includes combination chemotherapy and low-dose involved-field radiation (LD-IFRT). Because radiation may be ...
ascopubs.org5y
Bayesian Utility-Based Designs for Subgroup-Specific Treatment Comparison and Early-Phase Dose Optimization in Oncology Clinical Trials
Two Bayesian clinical trial designs that ... select the truly optimal dose in each subgroup. Table 4. Operating Characteristics of the NK Cell Dose-Finding Trial Design in a Scenario With ...
Yahoo Finance1mon
TransCode Therapeutics Reports Further Progress on Phase 1a Clinical Trial with No Dose Limiting Toxicities Reported in Patients with Metastatic Cancer
To date, 13 patients have received at least one dose of TTX-MC138 at 4 separate ... results and results from TransCode's Phase 0 clinical trial. Specifically, the preliminary PK data follow ...
Medicine Buffalo2y
Could low-dose lithium treat long COVID? UB launches clinical trial to find out
BUFFALO, N.Y. – Adults experiencing long COVID may be interested in a new University at Buffalo clinical trial that is testing low-dose lithium as a potential treatment. The randomized clinical trial ...
The New England Journal of Medicine3y
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes
In an open-label, 40-week, phase 3 trial, we randomly assigned 1879 patients, in a 1:1:1:1 ratio, to receive tirzepatide at a dose of 5 mg ... at doses up to 1 mg. In trials involving patients ...
Medicine Buffalo2y
Clinical trial aims to find out if low-dose lithium could treat long COVID
Adults experiencing long COVID may be interested in a new University at Buffalo clinical trial that is testing low-dose lithium as a potential treatment. The randomized clinical trial is recruiting 50 ...