This suggested something else must also be involved. Identification of candidate modifiers of lysosomal GCase activity through a genome-wide CRISPRi screen. (CREDIT: Science) ...

They did this work using a CRISPRi screen, which takes a guide RNA to a gene of interest and reduces its expression.

Results: Our CRISPRi screen identified 768 inhibitors of fibroblast activation and 818 genes that promote AdvFib activation (p-value < 0.05). Beyond the expected regulators of the cell cycle and other ...

For decades, researchers have wondered why some people with risky gene variants go on to develop Parkinson’s disease, while others do not. A new study may have just provided the most detailed answer ...

It's no wonder that screen protectors are already some of the most popular Switch 2 accessories. Switch 2 screen protectors come in a few different varieties, and some include cases.

As part of Apple's Liquid Glass redesign, announced at WWDC 2025, the new iOS 26 will rework some native Apple features and apps. Apple is also updating the Photos app, Safari, FaceTime, Phone ...

But in iOS 26, as part of the broader Liquid Glass redesign, album art gets a compelling new Lock Screen look. When playing any sort of media in iOS 26, there’s a fresh Lock Screen design for ...

If you encounter a Blue Screen when connecting to WiFi or Ethernet in Windows 11/10, the network driver might be corrupted. Use these fixes to resolve the issue.

Download 26 stunning 4K wallpapers for your iOS 26 lock screen. Handpicked for every style and mood, with direct download links for iPhones.

I am truly terrible at installing screen protectors, but thanks to dbrand's Prism 2.0, adding one to my Nintendo Switch 2 was a complete breeze.

If you’re anything like me, managing your kids’ screen time on phones, tablets, computers, game consoles – and even watches – can feel overwhelming. Today, children have a vast digital ...