Abstract Tu0067: A Genome-wide CRISPRi Screen Implicates Coronary Artery Disease GWAS Genes as Key Regulators of Adventitial Fibroblast Proliferation Arteriosclerosis, Thrombosis, and Vascular Biology ...

Conclusion: Our genome wide CRISPRi screen identified numerous potential regulators of AdvFib activation, many of which have known genetic and observational associations with human vascular diseases.

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These data, coupled with results from the CRISPRi radiosensitivity screen, identify pathways that offer potential insight into the mechanisms underlying intrinsic radioresistance and suggest biologic ...

Whole genome CRISPR interference (CRISPRi) screen was performed on MYCN and CMYC NESC-derived tumors and EV NESC. Viability in response to 72 hours of inhibitor treatment was analyzed qualitatively by ...

CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.

Breadcrumbs Salmonella-Typhimurium-CRISPRi-library-analysis / Script_S1_CRISPRi_Library_Screen_Sample_Analysis_R.R Copy path Blame Blame ...

By complementing CRISPRi with a Cas9 nuclease screen and transcriptional profiling, we identified promoters that control expression through their associated coding regions, as well as noncoding ...