Down syndrome babies generally have flat faces and very small noses, Nicolaides said. If the nasal bone shows up on an ultrasound at 12 weeks, he added, the infant is very unlikely to have the ...

An ultrasound scan could save many mothers ... Nearly two-thirds of 15-22-week-old fetuses with Down's syndrome lack a nasal bone, fetal-medicine specialist Kypros Nicolaides, of King's College ...

Soft markers are features that may be seen during a mid-pregnancy ultrasound ... likelihood of a Down syndrome diagnosis by 3–4 fold and that a small or absent nasal bone increased the ...

It was my worst nightmare at the time. An ultrasound found the fetus didn’t have a nasal bone, another marker of Down syndrome. Exactly one time, I was asked, “What do you want to do?” ...

It's also worth noting that Down syndrome is frequently linked to Binder's syndrome. According to reports, around 12% of patients with trisomy 21 do not have a nasal bone. The score is much higher ...