ISGylation induction decreases MVB numbers and impairs exosome secretion. Using ISG15-knockout mice and mice expressing the enzymatically inactive form of the de-ISGylase USP18, we demonstrate in ...

High centrifugal force can damage exosome integrity Charge neutralization-based precipitation (commercial kits) 32,33 Based on the principle of compound polymerization precipitation. Samples are mixed ...

However, ILVs also form in the absence of ESCRTs ... carry MHC-peptide complexes recognized by T lymphocytes. Secretion of those exosomes could promote antitumor immune responses.

A review led by Academician Yulong Yin from the Institute of Subtropical Agriculture of the Chinese Academy of Sciences has shed new light on the intricate interplay between exosomes and autophagy—two ...

Behold the future of your skin, hair, and body. The ELLE beauty team talked to experts to learn about the most exciting ...

A review led by Academician Yulong Yin from the Institute of Subtropical Agriculture of the Chinese Academy of Sciences has shed new light on the intricate interplay between exosomes and autophagy ...

"The phase-specific exosome secretion of LIFES meets physiological requirements, which aligns with the native multi-target and multi-stage paracrine regulation effects observed in physiological ...

Researchers have now identified a microRNA, miR-940, that is abundant in exosomes secreted by prostate cancer cells and can trigger bone-forming lesions in mice. The findings indicate that ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

Basically, exosomes are like a cell’s text message—but instead of words or emojis, they contain data in the form of proteins, lipids, growth factors, and RNA. “In skincare, exosomes are ...