To study exosomes in vivo, the team introduced pancreatic cancer cells into the peritoneal cavity of mice. One month later, they used immunohistochemistry to measure LAT1 expression in tumor tissue ...
The saccharide acts on exosome production by elevating levels of Ras-related protein 7 (Rab7). Trehalose SG also improves purification yields. Adding the saccharide suppresses exosome aggregation ...
ExosomeDx deploys its unique expertise to jointly solve a partner’s challenges and focuses on exosome-based RNA, protein and cfDNA analysis from any biofluid and from volumes as small as 0.5 ml.
Exosome-mediated small RNA-AGO2 transport and ... the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype ...
That concept sees INOVIQ being able to attach a chimeric antigen receptor (CAR) – a lab-created protein – to the exosomes produced by the NK cells. Those exosomes then targeted specific ...
Researchers have now found initial evidence that a blood test to detect the alpha-synuclein protein is a viable ... from neuronal cells (neuronal exosomes) from the blood and amplifying the ...
The fast and efficient process enables the characterization of 37 exosome surface markers in a single experiment. Studies indicate that the physiological significance of exosomes is not to be ignored.
US biotech PureTech Health has signed a potential billion-dollar deal with Roche based around its exosome technology that allows for oral administration of complex payloads – in this case ...