Sickle-cell anemia is due to a mutation in the gene encoding the β-subunit of hemoglobin (called HBB), which leads to an abnormal structure of the β-subunit protein chain and the sickle-cell ...

GYPA encodes a protein that the malaria parasite uses to enter blood cells. HBB is the gene responsible for sickle cell anemia in humans. This suggests that both chimpanzees and humans have ...

Zynext Ventures is investing in Illexcor Therapeutics to advance the clinical development of ILX002, its lead candidate for ...

Today, the cause of sickle cell disease is well understood to be a point mutation in a hemoglobin gene called HBB that makes red blood cells grow ... thanks to a massive physical model of the protein ...

It is caused by a mutation in the HBB gene, which leads to the production ... such as haematuria (blood in urine), proteinuria (excess protein in urine), and chronic kidney disease.