For the first time in his life, a young New Jersey man is pain-free thanks to a new gene treatment working to cure patients ...

Individuals with both sickle cell disease (SCD) and sickle cell trait are at higher risk than others of developing renal medullary cancer (RMC), the rarest and deadliest subtype of kidney cancer.

Sickle cell disease stems from a mutation in the gene that makes hemoglobin, the protein in red blood cells that carries oxygen throughout the body. Orkin’s team and others revealed that ...

Thirty-nine percent of those with verified hemoglobin SS genotype — the most severe type of sickle cell disease — were prescribed disease-modifying therapy. Overall, patients prescribed ...

Sickle cell disease is a genetic blood disorder caused by a single mutation in both copies of a gene coding for beta-globin. Beta-globin forms half of the oxygen-carrying molecule hemoglobin. This ...

Teenagers may reach puberty later than their friends. Sickle cell disease is caused by a problem in the hemoglobin-beta gene found on chromosome 11. The defect forms abnormal hemoglobin.

Sickle cell trait is not an illness ... they’ll do another test called a hemoglobin electrophoresis. This test can show what hemoglobin types you have and in what percentage.

The Food and Drug Administration has granted Orphan Drug designation to KIND Pharmaceutical’s AND017 for the treatment of sickle cell disease ... The hemoglobin elevating agent is being ...

Hemoglobin electrophoresis is the most common and definitive test for sickle cell disease. It involves separating the hemoglobin within red blood cells in a blood sample using an electric field.

Red blood cells are a marvel— not just for their incredible numbers in our body but also for what each of these cells carries inside it: hemoglobin ... happens in sickle cell disease.

Once he identified the cause of sickle cell as a mutant hemoglobin molecule, Pauling dubbed sickle cell anemia a “molecular disease.” That framing effectively launched the biomedical era of ...