Gupta's study identified a process that prevents progenitor cells from developing into fat cells in mouse subcutaneous inguinal fat. The protein HIF-1a (short for hypoxia-inducible factor-1 alpha ...

They assessed serum and tissues, as well as isolated cells from a fat deposit (inguinal) equivalent to human gluteal and thigh fat, for molecular and phenotypic changes, as well as metabolism ...

They focused in particular on a beige fat pad called the inguinal white adipose tissue ... a 0.03g difference in fat weight over a 25-30g mouse body weight," he told Live Science in an email.

Liu and colleagues 1 observed changes in resting energy expenditure, bone mineral density, and body composition in mice after 8 weeks of treatment with an antibody that blocked the binding of ...

In Gupta's mouse study, researchers used a genetic approach to inhibit HIF-1a and found that the progenitor cells could then make subcutaneous inguinal fat cells and fewer were inflamed or fibrotic.

Gupta's study identified a process that prevents progenitor cells from developing into fat cells in mouse subcutaneous inguinal fat. The protein HIF-1a (short for hypoxia-inducible factor-1 alpha ...