Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods ...

Hemifusomes are fused vesicles, or sacs of fluid, that were previously unknown to exist inside cells. They were discovered ...

SOB100 uses a gene-engineered exosome membrane embedded with nanobodies that bind to HLA-G, allowing for precise delivery of therapeutic agents in SOB100 to tumor cells while minimizing the systemic ...

A new study highlighting the importance of a large protein complex called the exocyst in cell growth, division and communication reveals new functions and mechanisms that are essential to how ...

In summary, the successful modulation of cholesterol content in exosome membranes to promote membrane fusion-mediated cargo transfer offers exciting opportunities for the development of safer and ...

MVBs can fuse with other vesicles and organelles in the cell, and the fusion of these MVBs (late endosomes) with the plasma membrane leads to the release of the exosomes into the extracellular space.

Exosomes are vesicles, or cellular components, that exist outside of a cell. They are generally understood as having been released from cells upon fusion with an intermediate endocytic compartment ...

The resultant intraluminal vesicle can then fuse with the plasma membrane and release exosomes and other mixed content. Autophagosomes and secretory lysosomes can fuse with the plasma membrane ...