Secreted vesicles known as exosomes were first discovered nearly 30 years ago. But, considered little more than garbage cans whose job was to discard unwanted cellular components, these small vesicles ...

"It's the first time a role for membrane fusion has been described for this complex and it's a breakthrough in how we think about the way the exocyst complex works," said Mary Munson, Ph.D ...

Evox is engineering exosomes—lipid-membrane-containing nanoparticles constitutively produced by cells—and loading them with protein therapeutics or nucleic-acid-based agents (Fig. 1).

Here we show in a human in vitro model system that exosomes, a population of small membrane vesicles secreted by living tumor cells, contain and transfer tumor antigens to dendritic cells.

Proteoliposomes were efficiently prepared by cell-free membrane protein synthesis with liposome chaperone (artificial cell method) for bio-analysis and DDS. New strategy for functionalization of ...

Exosome formation is a multistep process that begins with the inward budding of the plasma membrane to form early endosomes. These endosomes mature into multivesicular bodies (MVBs), which either ...