The house mouse, Mus musculus, is a small rodent and a classic vertebrate model organism for basic and biomedical research. It is attractive due to the existence of many well-characterized strains ...

Remember the time when the only way to alter expression of an endogenous gene in eukaryotes was to knock it out? Then came the discovery by Craig Mello and Andrew Fire in 1998 that a double ...

Whale species vary greatly in size. Some are just a few feet longer than a human, while others are the largest animals in the entire world. Whales also hold several records, such as being the largest ...

Background: The molecular function of a gene is most commonly inferred by sequence similarity. Therefore, genes that lack sufficient sequence similarity to characterized genes (such as certain classes ...

A review. Eukaryotic cells are complex structures capable of coordinating numerous biochem. reactions in space and time. Key to such coordination is the subdivision of intracellular space into ...