We present the first crystal structure of a Radical SAM enzyme, that of HemN, the Escherichia coli oxygen‐independent coproporphyrinogen III oxidase, at 2.07 Å resolution. HemN catalyzes the essential ...

Protoporphyrinogen IX oxidase (PPO), the last common enzyme of haem and chlorophyll ... Here we present the crystal structure of mitochondrial PPO from tobacco complexed with a phenyl‐pyrazol ...

Monoamine oxidase (MAO) is a useful target in the treatment of neurodegenerative diseases and depressive disorders. Understanding the structure-activity relationship (SAR) and mechanisms ...

NADPH oxidases (NOX) are transmembrane proteins, widely spread in eukaryotes and prokaryotes, that produce reactive oxygen species (ROS). Eukaryotes use the ROS products for innate immune defense and ...

the broader scientific community is continually working on understanding their intricate structure and function, leading to advances in formulating more efficient and stable versions of them. In ...

The resting phagocyte oxidase is a heterodimeric complex formed by two transmembrane proteins NOX2 and p22. Despite the physiological importance of this complex, its structure remains elusive. Here, ...

Thorsten Friedrich (University of Freiburg) have determined the molecular structure of the cytochrome bd oxidase from E. coli. This type of oxidase is found only in bacteria and microbial archaea.

A flat site structure is a website in which all pages are one click away from the home page. This strategy has existed for a long time. The founder of Pubcon, Brett Tabke (whom I regard as one of ...

D-Amino acid oxidase (DAAO) is an FAD-containing flavoenzyme that catalyzes ... roles during evolution and in different tissues in humans. Its three-dimensional structure is well conserved during ...

Successful propargylamine drugs such as deprenyl inactivate monoamine oxidase (MAO), a target in multi-faceted approaches to prevent neurodegeneration in the aging population, but the chemical ...