TFEB and TFE3 are two key transcription factors that regulate lysosomal biogenesis. TFEB/TFE3 links autophagy and lysosomal biogenesis through the transcriptional activation of genes involved in ...

Opening this channel on acidic vesicles releases protons, increasing the pH inside the vesicles and activating TFEB. Dr. Yan and his colleagues hypothesize that because lysosomes normally degrade ...

Family flowers only please donations in lieu to PSPA and North Northumberland Hospice, Alnwick Dress code a splash of colour. (Joe) (Burnopfield) Formerly of Whickham. Peacefully in hospital on ...

the company wrote. Emergency as flooding affects homes Queensland Police issued an emergency declaration under the Public Safety Preservation Act (PSPA) for Adavale, a tiny rural town west of Roma ...

The Drexel University Physician Assistant program will maintain excellence in educating competent physician assistant students, emphasizing integrity, respect for diversity, teamwork, patient advocacy ...

Queensland Police issued an emergency declaration under the Public Safety Preservation Act (PSPA) for Adavale, a tiny rural town west of Roma, about 8.15am on Thursday. “Emergency services have ...

Loved ones have paid tribute to a Cleveland Police detective sergeant and a former magistrates' court worker in The Gazette death and funeral notices this week. Announcing the passing of a loved ...