This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

Although osteoarthritis is receiving more attention in both the research and clinical arenas than ever, all that attention ...

"I can't do my daily life because my fingers are stiff in the morning"The stiffening of the finger joints in the morning ...

When the synovium grows too bulky, it produces too much synovial fluid, which contains an enzyme that, in large quantities, “eats away” at the articular cartilage on the joint surface. In patients ...

Articular cartilage degeneration and other features of OA ... Ultrasound is extremely sensitive for identifying synovial cysts that sometimes form in joints which have osteoarthritis. It is also ...

The symptoms of osteoarthritis include inflammation of synovial joints, osteophyte formation and articular cartilage degeneration. Although, clear understanding of the causes of osteoarthritis remains ...

Generally speaking, many people experience some joint stiffness, which is often most severe when first rising in the morning.

Q. What causes joint pain? A. Your joints are made up of bone, cartilage and synovial fluid. As we age, cartilage starts to break down and our bodies start to produce less synovial fluid.

The successful treatment of focal full-thickness articular defects of the knee has ... chondral defects frequently have persistent joint line pain, swelling, and catching in the knee.

The term osteoarthritis refers to a group of disorders that result in the primarily mechanically induced structural and functional failure of synovial joints. Modifications enhancing degradation ...