While Emma has Down syndrome — specifically a rare type called Mosaic Down syndrome — some people don’t believe it. “At the ...

In addition to genetic modifiers of Aβ and tau pathologies, other factors likely modulate the expression of AD in DS individuals. For example, trisomy 21-associated alterations in brain structure, ...

World Down Syndrome Day aims to raise awareness about the condition and ways to manage it. Down Syndrome is a genetic ...

On World Down Syndrome Day, March 21, we remember Dr. Jérôme Lejeune, a Catholic doctor on his way to sainthood.

Down Syndrome, known as Trisomy 21, is a genetic disorder caused by an extra chromosome 21. It affects facial appearance, ...

Ashley Zambelli had three kids who tested positive for trisomy 21 — then she found out that ... her three kids — she shares their specific genetic mutation, too. TikTok creator Ashley Zambelli ...

On March 21, 2025, the world observes the 14th World Down Syndrome Day (WDSD), a day dedicated to raising public awareness ...

Ryotaro Hashizume and colleagues use the CRISPR-Cas9 gene editing system to cleave the third chromosome in previously generated trisomy 21 cell lines derived from both pluripotent cells and skin ...

I gave birth to a beautiful baby girl with almond shaped eyes,” a woman named Sarah wrote on Cincinnati Children’s Hospital’s website. “The doctors and nurses didn’t notice, but I did. After days of ...

Decades ago, researchers showed that Down syndrome (also known as trisomy 21), was caused when individuals carried an extra copy of chromosome 21. Down syndrome is also the most common genetic cause ...

Why does the total number of chromosomes in a cell matter? Learn how chromosomes self-organize within single cells, and how these patterns help us detect genetic defects.