An informed consent was signed by the parents at enrollment. A second tympanocentesis was performed on Days 4 to 6 (72 to 120 h after initiation of therapy) in patients with positive initial ...
Patients and Methods: From 1995 through 2000, 1077 infants and young children ages 3 to 36 months with AOM were enrolled in double tympanocentesis (performed on Day 1 in all patients and Days 4 to ...