Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

Edited* by Xiaodong Wang, University of Texas Southwestern Medical Center, Dallas, TX, and approved September 7, 2010 (received for review June 24, 2010) ...

lysosome-associated membrane protein 2A. UPS-mediated protein degradation consists of 2 main steps: ubiquitination of a target protein molecule and degradation of the ubiquitinated protein by the ...

This study aimed to investigate lysosome damage-induced major transcriptional responses and the underlying signaling basis. The authors have convincingly shown that lysosomal damage activates a ...

Denmark is planning to spend over $1.5 billion to protect Greenland. WSJ explains how dogsleds and drones will bolster defenses—and why the U.S. abandoned several military bases there decades ago.

And urging Europe to step up its game, he said AstraZeneca will shift manufacturing across the Atlantic to avoid tariffs on pharma imports planned by Donald Trump. ‘When you see the amount of ...

Rubio Says Concrete Ukraine Proposals Needed Now, or US Will Step Back By Daphne Psaledakis and David Brunnstrom WASHINGTON (Reuters) - U.S. Secretary of State Marco Rubio said on Tuesday that now ...

Shin Bet chief Ronen Bar said he intended to leave his role on 15 June The head of Israel's Shin Bet domestic intelligence agency has resigned. Ronen Bar made the announcement that he would leave ...

We love:Cetaphil Gentle Skin Cleanser, £11.50. "SPF is a non-negotiable step during the day to protect against UV damage and premature ageing, regardless of skin type," says Dr Ahmed. Chemical ...