KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat. In ...

High-grade gliomas, such as GBM, characteristically break this barrier, and that is easily observed in imaging studies such as a MRI. Neurosurgical procedures also disrupt the BBB, which may ...

Glioblastoma Multiforme (Frontal Lobe). T1-weighted axial MRI. Note the large mass in the deep left frontal lobe with central necrosis and surrounding edema. Also note the prominent enhancement with ...

morphological features and MRI histogram analysis in noninvasively predicting Ki-67 expression levels in patients with IDH-wildtype glioblastoma. Methods: Forty-six cases of IDH-wildtype glioblastoma ...

China Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, Changchun 130024, China Center for AIE Research, ...

Abstract: Glioblastoma (GBM), a common cancer of the central nervous system (CNS), is considered incurable worldwide. The treatment of GBM varies from patient to patient, as conventional medical ...

dNeuroradiological Academic Unit, University College London Queen Square Institute of Neurology, University College London, London, UK eFaculty of Brain Sciences, University College London Queen ...

Important step towards improving diagnosis and treatment of brain metastases First standardized criteria for the use of amino acid PET published Date: May 8, 2025 Source: Medical University of ...

Inhibition of the epidermal growth factor receptor (EGFR) shows clinical benefit in metastatic colorectal cancer (CRC) patients, but KRAS-mutations are known to confer resistance. However, recent ...

"We are pleased to expand our portfolio of licensed patents and add a technology that uses REQORSA to treat glioblastoma," said Thomas Gallagher, Senior Vice President of Intellectual Property and ...

Newly discovered oncology drugs called “DNA-encoded tri-specific T-cell engagers,” or “DTriTEs,” engage the immune system more effectively than traditional therapies, particularly against evasive and ...