McCaffrey stayed healthy in 2023, finishing with a league-leading and career-high 1,459 rushing yards and 14 touchdowns. His 2,023 yards from scrimmage and 21 total touchdowns led the NFL, as the 49ers reached Super Bowl 58. There, they fell to the Kansas City Chiefs in overtime.

That's why NFL.com says the 49ers' No. 1 offseason priority is to prepare those young defenders to carry a hefty load.

The San Francisco 49ers gave Brock Purdy a huge extension earlier this month. Now, he has to prove that he's worth the payday.

The Philadelphia Eagles are trading Pass rusher Bryce Huff to the San Francisco 49ers following this year's Super Bowl win.

It was starting to become a serious concern for the San Francisco 49ers when they were undergoing their search for a new defensive coordinator. The writing was

The San Francisco 49ers took Mykel Williams in the first round of the 2025 NFL draft, and analysts predict that pick could pay off in his first year.

SANTA BARBARA, Calif. - Mitch Wisnowsky is looking for a new NFL home after the San Francisco 49ers released the 33-year old punter. Wishnowsky was a

Second-year wide receiver Ricky Pearsall tweaked his hamstring and is unlikely to return to the field until training camp, per Eric Branch of the San Francisco Chronicle. Since Brandon Aiyuk is still recovering from a torn ACL and MCL in his right knee,