This series of systematic reviews was commissioned by WHO in July 2022 to inform their guideline review process. The aim was to identify the current evidence for developing WHO guidelines for the ...

Conclusion Consumption of slush ice drinks containing glycerol may cause a clinical syndrome of glycerol intoxication in young children, characterised by decreased consciousness, hypoglycaemia, lactic ...

Objective To evaluate the impact of an integrated child health system. Design Mixed methods service evaluation. Setting and patients Children, young people and their families registered in Child ...

Objective The aim of this research was to ascertain the effectiveness of current electronic prescribing (EP) systems to prevent a standardised set of paediatric prescribing errors likely to cause harm ...

Objective To report the diagnostic test accuracy of dipstick urinalysis for the detection of urinary tract infections (UTIs) in febrile infants aged 90 days or less attending the emergency department ...

Rationale Studies suggest that increased breastfeeding rates can provide substantial financial savings, but the scale of such savings in the UK is not known. Objective To calculate potential cost ...

Objective: The 6-minute walk test (6MWT) is an established measure of exercise capacity in adults and children with chronic cardiac or respiratory disease. Despite its widespread use, there are no ...

Chronic pain is an important clinical problem affecting significant numbers of children and their families. The severity and impact of chronic pain on everyday function is shaped by the complex ...

Aim Following the publication of the updated NICE guidelines1 recommending the use of standardised parenteral nutrition (PN) in preterm and term babies, alongside the known associated risks to patient ...

Background Cognitive ability and socioemotional behaviour during childhood have independently been shown to impact educational outcomes. The extent to which their co-development predicts these ...

Childhood encephalopathy is an uncommon but significant paediatric presentation and is associated with significant mortality and long-term morbidity in survivors. By definition it is a somewhat ...

Objective Routine varicella zoster vaccination for children aged 18 months began in Australia from November 2005. The aim of this study was to compare the current incidence and outcomes of congenital ...