The intrinsic factor of cell senescence, PCBP2, was identified by unlabeled quantitative proteomics, and its biological role in in vitro replication senescence of human bone marrow mesenchymal stromal ...

Here, we found that inhibition of AMPK occurs during naïve transition with two conventional inhibitors of the MEK1 and GSK3β pathways. The accumulation of glycogen due to iGSK3β is responsible for ...

Icaritin (ICA) is a prenylflavonoid natural product extracted from plants of the Epimedium genus. The approval of ICA softgel capsules as a class 1.2 traditional Chinese medicine (TCM) innovative drug ...

The tumor suppressor p53, a stress-induced transcription factor, can inhibit cell growth and proliferation via its target genes, such as the cyclin-dependent kinase (CDK) inhibitor p21, which serves .

rabbit anti-phosphor-AMPK (α, phospho Thr172; 1:200, Abcam, ab23875), rabbit anti-phospho-histone H2AX (phospho Ser139; 1:200, Abcam, ab2893), rabbit anti-phospho-histone H3 (phospho Ser10; 1:600, ...