BONE changes in frostbitten extremities have been described only rarely in the medical literature, and before World War II, most cases documented by radiographic studies were from Europe.

Pycnodysostosis is a rare, autosomal recessive genetic condition, which causes a decrease in bone remodeling, resulting in different clinical and radiographic manifestations. This case series aims to ...

Skin hypertrophy (pachydermia). Thickening of facial features, up to the formation of characteristic folds of the hairy scalp and forehead (the so-called lion’s ...

Diagnosis of picnodystosis was made clinically by the presence of Wormian bones in the skull, micrognathia, clavicular hypoplasia, acroosteolysis, osteosclerosis and increased bone density in long ...

Local priming of osteoclast precursors (OCp) has long been considered the main and obvious pathway that takes place in the human body, where local bone lining cells and RANKL-expressing osteocytes may ...

Since prostaglandin is likely to be involved in periosteal bone formation and acroosteolysis this explains why non-steroidal anti-inflammatory drugs and steroids are useful in alleviating arthritis [2 ...

We conclude that brachyonychia and acroosteolysis in chronic kidney disease suggest long-term disease, secondary hyperparathyroidism, and hemodialysis, besides it being a good model on how the bony ...

We report a 9-year-old Saudi boy who was seen in rheumatology clinic after referral due to abnormal skin pigmentation and flexing contractures of his extremities. His parents are first degree ...

A vast number of conditions ranging from simple trauma to hereditary and collagen vascular disease had been described in association with acroosteolysis. Lab investigations including Parathormone ...

1 HOA includes skin manifestations such as thickened skin on face and scalp, and coarse facial features along with clubbing, periostosis, acroosteolysis, and painful joint motion. 6 HOA may be ...