"Through experiments conducted on cultured podocytes, we have demonstrated, for the first time that membrane raft-associated redox signaling is essential for the NLRP3 inflammasomes assembly and ...

With this system, podocytes taken from isolated glomeruli, the filtering units of the kidney, can be cultured on patterns of the proteins that would be in their vicinity in healthy and diseased ...

In a poster titled, ‘Comparative transcriptomic analysis of cultured podocytes and human kidney organoids at single cell-resolution,’ Goldfinch Bio researchers describe the advancement of a ...

"We found that transmembrane TNF-alpha facilitates the low level productive infection of podocytes cultured from HIV-positive children and renal tubular epithelial cells that do not express CD4 ...

The research, led by a team from the Medical University of Vienna in Austria, found that high blood pressure can lead to abnormalities in the podocytes -- specialised cells in the renal filter ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “Inhibiting NLRP3 signaling in aging ...

The gene therapy, called PS-002, uses a modified virus to treat kidney cells called podocytes. Administration of PS-002 in a mouse model of IgA nephropathy reduced signs of kidney dysfunction ...