Computational study shows how apical carbons in propellanes and pyramidanes can form hydrogen, halogen, chalcogen, pnictogen ...

State Key Laboratory of Petroleum Molecular & Process Engineering, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal ...

The site-selectivity classification task is optimized alongside with two molecular property regression tasks of reaction substrates (arene and electrophile). These two regression tasks which is ...

Both of the new reactions are cross-electrophile couplings, which wed two different electrophiles. Although there ways to do cross-electrophile couplings using chemical reagents, these ...

1 Centro de Química Médica, Instituto de Ciencias e Innovación en Medicina, Clínica Alemana Universidad del Desarrollo, Santiago, Chile 2 Facultad de Química y de Farmacia, Pontificia Universidad ...

Since native electrophile signaling in vivo proceeds as a diffusion-limited second-order reaction between a specific electrophile and a protein of interest (POI) (2), our approach gives a very clear ...

In this perspective, we first overview emerging toolsets that can decode electrophile-signaling events in a protein/context-specific manner, and how the accumulating mechanistic insights brought about ...

When the labile bond between the Mida ligand’s nitrogen and the boron is broken, it reacts like other boron compounds – as an electrophile. In this state, Mida boronates undergo 1,4-shift reactions ...

Figure 6: HS − regulation of H-Ras electrophile sensing and signaling. Figure 8: Dissociation of H-Ras from rafts and its activation induced by H-Ras Cys184 S-guanylation. In conclusion ...