To study exosomes in vivo, the team introduced pancreatic cancer cells into the peritoneal cavity of mice. One month later, they used immunohistochemistry to measure LAT1 expression in tumor tissue ...

The saccharide acts on exosome production by elevating levels of Ras-related protein 7 (Rab7). Trehalose SG also improves purification yields. Adding the saccharide suppresses exosome aggregation ...

ExosomeDx deploys its unique expertise to jointly solve a partner’s challenges and focuses on exosome-based RNA, protein and cfDNA analysis from any biofluid and from volumes as small as 0.5 ml.

Furthermore, the study underscores the important role of the Alix protein in Sr-induced miRNA selectively loading, pointing to Alix-mediated mechanisms as critical for optimizing exosome therapy.

Secreted vesicles known as exosomes were first discovered nearly 30 years ago. But, considered little more than garbage cans whose job was to discard unwanted cellular components, these small vesicles ...

Researchers have now found initial evidence that a blood test to detect the alpha-synuclein protein is a viable ... from neuronal cells (neuronal exosomes) from the blood and amplifying the ...

Furthermore, the study underscores the important role of the Alix protein in Sr-induced miRNA selectively loading, pointing to Alix-mediated mechanisms as critical for optimizing exosome therapy.

Combined with the purification and filtration device, high purity exosome particles can be obtained quickly and efficiently, which can be used for electron microscopy, NTA particle size analysis, ...

In addition to its well-known role as a protein chaperone, Hsp90 stimulates exosome release. These findings shed new light on treatment strategies for both cancer and neurodegenerative diseases. Two ...

That concept sees INOVIQ being able to attach a chimeric antigen receptor (CAR) – a lab-created protein – to the exosomes produced by the NK cells. Those exosomes then targeted specific ...