T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response ...

Tsingke has delivered high-quality biotechnology services and products to nearly 300,000 users globally. The number of high-level academic papers published ...

Inhibition of CDK6 may prevent arteriovenous malformations in hereditary hemorrhagic telangiectasia by regulating endothelial ...

affecting the cell cycle progression of the neural stem cells, leading to cell death of newborn neurons. "The SVZ stem cell niche is a fragile system. Microglia, the defense cells of the brain ...

Circle Pharma, a clinical-stage biopharmaceutical company dedicated to discovering and developing a new generation of macrocycle therapies, today announced that preclinical data from its lead ...

The pre-clinical data shows CID-078 demonstrated single-agent tumor activity across tumor cell line and in vivo models with dysregulated cell cycle (CDK-RB-E2F) function. Notably, tumor ...

This is an important study on the damage-induced checkpoint maintenance and termination in budding yeast that provides novel and convincing evidence for a role of the spindle assembly checkpoint and ...

The Gaublomme lab has developed a new optical pooled screening approach called CRISPRmap, which enables the coupling of optical properties of single cells to targeted genetic perturbations.

This study explores the prognostic significance of tumor-draining lymph nodes (TDLNs) in OSCC, with a special focus on the quantification of T regulatory cells (Tregs) and the expression of immune ...