“To address this challenge, we develop a machine learning (ML)-guided platform that integrates cell-free DNA assembly, cell-free gene expression, and functional assays to rapidly map fitness ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Moscot is a cell-mapping framework based on the concept ... so only a few modalities (cell characteristics such as gene expression, chromatin accessibility and surface proteins) can be measured ...

where NRF2 is activated and it promotes gene expression to make proteins that will combat that oxidative insult. The Chang Lab's work steps into this arena, bridging sensing and catalysis to map ...

where NRF2 is activated and it promotes gene expression to make proteins that will combat that oxidative insult. The Chang Lab's work steps into this arena, bridging sensing and catalysis to map ...

Max Planck Institute for Biological Intelligence researchers have identified over 60 transcriptomic neuron types in the ...

An international team of researchers has, for the first time, created a detailed map of the location and identity of individual cells in the adult lung, both from healthy lungs and in lungs from ...

Hutton scientists who have been leading a 48-strong international consortium, have found that different strains have very different patterns of switching genes on and off (known as gene expression).

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...