Quetiapine (Seroquel) was more clinically effective than lithium as a first-line augmentation option in treatment-resistant depression and likely was more cost-effective, a pragmatic multicenter ...

"Compared with lithium, quetiapine might be a more appropriate first-line augmentation for many people with treatment-resistant depression. Future research should investigate predictors of ...

Doctors may prescribe lithium, an antimanic drug, or an antipsychotic drug -- or a combination of both -- in order to alleviate symptoms of depression without triggering a manic episode.

lithium, or another antidepressant agent, or a switch to a different class of agent. Referral for a psychiatric evaluation for consideration of electroconvulsive therapy or other treatment is ...

In this phase, patients taking antidepressants such as Prozac, Lexapro and Zoloft were treated with lithium or nortriptyline -- medications that were widely used before those other, newer ...

Traditional antidepressants are considered "experimental" for treating bipolar depression in that none has been proven to be more effective than a placebo (sugar pill) in bipolar I disorder.

Lithium is a mood-stabilizing medication commonly used to treat bipolar disorder, says Wragg. It’s also sometimes used alongside an SSRI for treatment-resistant depression to help the SSRI work ...

Augmentation was more effective with quetiapine than lithium for treatment-resistant depression in a pragmatic trial. Quetiapine also improved quality-adjusted life years more than lithium.